Recapitulating Early Development Of Mouse Musculoskeletal Precursors Of The Paraxial Mesoderm In Vitro. Chal J, Al Tanoury Z, Oginuma M, Moncuquet P, Gobert B, Miyanari A, Tassy O, Guevara G, Bera A, Sumara O, Garnier JM, Kennedy L, Knockaert M, Gayraud-Morel B, Tajbakhsh S and Pourquié O. Development, in press. Also deposited on Biorxiv: http://www.biorxiv.org/content/early/2017/05/22/140574. doi: 10.1101/140574.

Lancet Commission: Stem Cells and Regenerative Medicine. Cossu G, Birchall M, Brown T, De Coppi P, Culme-Seymour E, Gibbon S, Hitchcock J, Mason C, Montgomery J, Morris S, Muntoni F, Napier D, Owji N, Prasad A, Round J, Saprai P, Stilgoe J, Thrasher A and Wilson J. Lancet, 2018 Mar 3; 391 (10123):883-910. Epub 2017 Oct 4. PMID: 28987452

Reversible Immortalisation Enables Genetic Correction of Human Muscle Progenitors and Engineering of Next-Generation Human Artificial Chromosomes for Duchenne Muscular Dystrophy. Benedetti S, Uno N, Hoshiya H, Ragazzi M, Ferrari G, Kazuki Y, Moyle LA, Tonlorenzi R, Lombardo A, Chaouch A, Mouly V, Moore M, Popplewell L, Kazuki K, Katoh M, Naldini L, Dickson G, Messina G, Oshimura M, Cossu G and Tedesco FS. EMBO Molecular Medicine, 2018 Feb; 10(2): 254-275. PMID: 29242210

Muscle Interstitial Cells: A Brief Field Guide to Non-satellite Cell Populations in Skeletal Muscle. Tedesco FS, Moyle LA and Perdiguero E. Methods in Molecular Biology, 2017; 1556: 129-147. PMID: 28247348.

Generation of three-dimensional human artificial skeletal muscle tissue from iPS cells enables complex disease modelling for muscular dystrophy. Maffioletti SM, Henderson ABH, Sarcar S, Mannhardt I, Pinton L, Steele-Stallard H, Moyle LA, Ragazzi M, Wang W, Zammit P, Eschenhagen T and Tedesco FS. Human Gene Therapy, Dec 2017, 28(12): A1-A125. Epub 2017 Oct 17. PMID: 29037080.

Combined Notch and PDGF signalling in muscle satellite cells induces a pericyte-like phenotype with potential cell therapy relevance. Moyle LA, Gerli MFM, Ucuncu E, Louca I, Constantinou C, Sakai H, Ragazzi M, Tajbakhsh S, Cossu G and Tedesco FS. Human Gene Therapy, Dec 2017, 28(12): A1-A125. Epub 2017 Oct 17. PMID: 29037080.

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes. Schwach V, Verkerk AO, Mol M, Monshouwer-Kloots JJ, Devalla HD, Orlova VV, Anastassiadis K, Mummery CL, Davis RP and Passier R. Stem Cell Reports, 2017 Dec 12;9(6):1765-1779. Epub 2017 Nov 22. PMID: 29173897.

Generation of biocompatible human artificial 3D skeletal muscle tissue from healthy and dystrophic pluripotent stem cells. Maffioletti S, Henderson, A, Sarcar S, Manhardt I, Moyle L, Ragazzi M, Wang W, Eschenagen T and Tedesco FS. Neuromuscular Disorders, Oct 2017; 27(S2), pp. S213.

Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions. Hackland JOS, Frith TJR, Thompson O, Marin Navarro A, Garcia-Castro MI, Unger C and Andrews PW. Stem Cell Reports, 2017 Oct 10;9(4):1043-1052. Epub 2017 Sep 14. PMID: 28919261.

Epigenetic resetting of human pluripotency. Guo G, von Meyenn F, Clarke J, Rostovskaya M, Myers S, Baker D, Sahakyan A, Plath K, Reik W, Bertone P and Smith A. Development, 2017 Aug 1; 144 (15): 2748-2763. PMID: 28765214.

Making muscle: skeletal myogenesis in vivo and in vitro. Chal J and Pourquié O. Development, 2017 Jun 15; 144(12): 2104-2122. PMID: 28634270.

Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo. Pievani A, Sacchetti B, Corsi A, Rambaldi B, Donsante S, Scagliotti V, Vergani P, Remoli C, Biondi A, Robey PG, Riminucci M and Serafini M. Development, 2017 Mar 15; 144(6): 1035-1044. PMID: 2829284.

Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells. Giacomelli E, Bellin M, Sala L, van Meer BJ, Tertoolen LGJ, Orlova VV and Mummery CL. Development, 2017 Mar 15; 144 (6): 1008-1017. PMID: 28279973.

Generation of implantable 3D skeletal muscle tissue from human embryonic stem cells and muscular dystrophy iPS cells. Maffioletti SM, Vollert I, Henderson A, Ragazzi M, Wang W, Eschenhagen T, Tedesco FS. Human Gene Therapy; 2016 Nov; 27(11): A1-A185. Epub 2016 Oct 17. PMID: 27749099.

Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro. Chal J, Al Tanoury Z, Hestin M, Gobert B, Aivio S, Hick A, Cherrier T, Nesmith AP,Parker KK and Pourquié O. Nature Protocols, 2016 Oct; 11 (10): 1833-50. Epub 2016 Sep 1. PMID: 27583644.

No Identical “Mesenchymal Stem Cells” at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels. Sacchetti B, Funari A, Remoli C, Giannicola G, Kogler G, Liedtke S, Cossu G, Serafini M, Sampaolesi M, Tagliafico E, Tenedini E, Saggio I, Robey PG, Riminucci M, Bianco P. Stem Cell Reports, 2016 Jun 14; 6 (6): 897-913. PMID: 27304917

RAC-tagging: Recombineering And Cas9-assisted targeting for protein tagging and conditional analyses. Baker O, Gupta A, Obst M, Zhang Y, Anastassiadis K, Fu J and Stewart AF. Scientific Reports, 2016 May 24; 6:25529; PMID: 27216209.

Stem cell niche engineering through droplet microfluidics. Allazetta S and Lutolf MP. Current Opinion in Biotechnology, 2015 Dec; 35: 86-93. Epub 2015 Jun 4. PMID: 26051090.

Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva. Cai J, Orlova VV, Cai X, Eekhoff EM, Zhang K, Pei D, Pan G, Mummery CL, Ten Dijke P. Stem Cell Reports, 2015 Dec 8; 5(6): 963-70. Epub 2015 Nov 26. PMID: 26626181.

Cell‐Instructive Microgels with Tailor‐Made Physicochemical Properties. Allazetta S, Kolb L, Zerbib S, Bardy J and Lutolf MP. Small; 11 Nov 2015; 11(42): 5647-56. Epub 2015 Sep 9. PMID: 26349486.

Substrate elasticity modulates the responsiveness of mesenchymal stem cells to commitment cues. Gobaa S, Hoehnel S and Lutolf MP. Integrative Biology, 2015 Oct; 7(10): 1135-42. Epub 2015 Mar 9. PMID: 25749492.

Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy. Chal J, Oginuma M, Al Tanoury Z, Gobert B, Sumara O, Hick A, Bousson F, Zidouni Y, Mursch C, Moncuquet P, Tassy O, Vincent S, Miyanari A, Bera A, Garnier JM, Guevara G, Hestin M, Kennedy L, Hayashi S, Drayton B, Cherrier T, Gayraud-Morel B, Gussoni E, Relaix F, Tajbakhsh S, Pourquié O. Nature Biotechnology, 2015 Sep; 33 (9): 962-9. Epub 2015 Aug 3. PMID: 26237517.

Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells. Birket MJ, Ribeiro MC, Verkerk AO, Ward D, Leitoguinho AR, Hartogh SC, Orlova VV, Devalla HD, Schwach V, Bellin M, Passier R and Mummery CL. Nature Biotechnology, 2015 Sep; 33 (9): 970-9. Epub 2015 Jul 20. PMID: 26192318.

Efficient derivation and inducible differentiation of expandable skeletal myogenic cells from human ES and patient-specific iPS cells. Maffioletti SM, Gerli MFM, Ragazzi M, Dastidar S, Benedetti S, Loperfido M, Driessche TV, Chuah MK and Tedesco FS. Nature Protocols, 2015 Jul; 10 (7); 941-58. Epub 2015 Jun 4. PMID: 26042384.

Osteoblast-specific expression of the Fibrous Dysplasia (FD) causing mutation, GsαR201C produces a high bone mass phenotype but does not reproduce FD in the mouse. Remoli C, Michienzi S, Sacchetti B, Di Consiglio A, Cersosimo S, Spica E, Robey PG, Holmbeck K, Cumano A, Boyde A, Davis G, Saggio I, Riminucci M and Bianco P. Journal of Bone and Mineral Research, 2015 Jun; 30 (6): 1030-43. PMID: 25487351. Gold open access

Culture adaptation alters transcriptional hierarchies among single human embryonic stem cells reflecting altered patterns of differentiation. Gokhale P, Au-Young JK, Dadi SV, Keys DN, Harrison NJ, Jones M, Soneji S, Enver T, Sherlock JK, Andrews PW. PLoS One, 2015 Apr 14; 10 (4):e0123467. PMID: 25875838.

Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes. Eschenhagen T, Mummery C and Knollmann BC. Cardiovascular Research, 2015 Apr 1; 105 (4): 424-38. PMID: 25618410.

Skeletal Stem Cells. Bianco P and Robey PG. Development, 2015 Mar 15; 142 (6): 1023-7. PMID: 25758217.

PW1/Peg3 expression regulates key properties that determine mesoangioblast stem cell competence. Bonfanti C, Rossi G, Tedesco FS, Giannotta M, Benedetti S, Tonlorenzi R, Antonini S, Marazzi G, Dejana E, Sassoon D, Cossu G, Messina G. Nature Communications, 2015 Mar 9; 6: 6364. PMID: 25751651.

Human artificial chromosomes for Duchenne muscular dystrophy and beyond: challenges and hopes. Tedesco FS. Chromosome Research, 2015 Feb; 23 (1): 135-41. PMID: 25596829.

Stem cells and bone diseases: new tools, new perspective. Riminucci M, Remoli C, Robey PG and Bianco P. Bone, 2015 Jan; 70: 55-61. PMID: 25240458.

Stem cells and bone: a historical perspective. Bianco P. Bone, 2015 Jan; 70: 2-9. PMID: 25171959.

Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders. Balakumaran A, Mishra PJ, Pawelczyk E, Yoshizawa S, Sworder BJ, Cherman N, Kuznetsov SA, Bianco P, Giri N, Savage SA, Merlino G, Dumitriu B, Dunbar CE, Young NS, Alter BP and Robey PG. Blood, 2015 Jan 29; 125 (5): 793-802. PMID: 25499762.

Stem cell transplantation for muscular dystrophy: the challenge of immune response. Maffioletti SM, Noviello M, English K, Tedesco FS. BioMed Research International, 2014; 2014:964010. PMID: 25054157.

Constitutive expression of Gsα (R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history. Saggio I, Remoli C, Spica E, Cersosimo S, Sacchetti B, Robey PG, Holmbeck K, Cumano A, Boyde A, Bianco P and Riminucci M. Journal of Bone and Mineral Research, 2014 Nov; 29 (11): 2357-68. PMID: 24764158.

Resetting transcription factor control circuitry toward ground state pluripotency in human. Takashima Y, Guo G, Loos R, Nichols J, Ficz G, Krueger F, Oxley D, Santos F, Clarke J, Mansfield W, Reik W, Bertone P and Smith A. Cell, 2014 Sep 11; 158 (6): 1254-1269. PMID 25215486.

“Mesenchymal” stem cells. Bianco P. Annual Review of Cell and Developmental Biology, 2014 Oct; 30: 677-704. PMID 25150008.

Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells. Orlova VV, van den Hil FE, Petrus-Reurer S, Drabsch Y, ten Dijke P and Mummery CL. Nature Protocols, 2014 May 29, 9 (6): 1514-31. PMID: 24874816.

Hydrogel microfluidics for the patterning of pluripotent stem cells. Cosson S and Lutolf MP. Scientific Reports, 2014 Mar 25; 4: 4462. PMID: 24662945.