An international Scientific Advisory Panel (SAP) will provide high level input and guidance to PluriMes. The SAP comprises leading experts in the fields of stem cell and developmental biology, bioengineering, mesenchymal stromal cells, quality control and regulation. The following distinguished scientists have agreed to be members of the PluriMes SAP:
Professor Margaret Buckingham (Chair); Institut Pasteur, France
Margaret Buckingham is a Professor Emeritus at the Institut Pasteur, where she is part of the Molecular Genetics of Development Unit. Margaret’s work has focused on the regulation of cell fate choices, and subsequently, of the self-renewal versus differentiation of a cell that has entered a tissue specific lineage, which are key aspects of stem cell biology. In adult tissues, maintenance of stem cells and their contribution to regeneration are also major concerns. Margaret's laboratory addressed these issues in the context of skeletal muscle.
Dr Pamela Robey; National Institute of Dental and Craniofacial Research, National Institutes of Health, USA
Pamela Robey is Chief in the Craniofacial and Skeletal Diseases Branch at the National Institute of Dental and Craniofacial Research. The Skeletal Biology Section has a long-term interest in defining the biological properties of post-natal skeletal stem cells (SSCs) with a particular emphasis on determining the role that they play in the pathophysiology of skeletal diseases, and how they can be used in tissue engineering and regenerative medicine.
Dr Glyn Stacey; UK Stem Cell Bank, National Institute for Biological Standards and Controls, United Kingdom
Glyn Stacey is Director of the UK Stem Cell Bank, which prepares stem cell lines for use worldwide in research and in the development of new therapies for human diseases. He is engaged in initiatives on the standardisation of stem cell culture including the International Society for Stem Cell Research (standards committee) and the International Stem Cell Initiative.
Professor Shahragim Tajbakhsh; Institut Pasteur, France
Shahragim Tajbakhsh is part of the Stem Cells and Development Unit at the Pasteur Institut. The aim of Shahragim’s lab is to characterise stem cells and their daughters during embryonic and postnatal development of skeletal muscle to understand how this tissue is established, and how it regenerates. They are examining the genetic networks which regulate myogenic stem cell emergence, and relating this to how cell order is established in this lineage.
Professor Peter Zandstra; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Canada
Peter Zandstra holds an academic appointment as a Professor at the University of Toronto’s Institute of Biomaterials and Biomedical Engineering. He is cross appointed with the Departments of Chemical Engineering and Applied Chemistry and Medical Genetics and is the Canadian Research Chair in Stem Cell Bioengineering. Peter's work integrates engineering and biological approaches and has contributed to the development of clinically and industrially relevant and academically recognized technologies based on the design of bioprocesses for the growth and differentiation of adult and embryonic stem cells. Direct applications of this work include tissue and cellular engineering, gene therapy, and organ transplantation.